CLARA represents the interdisciplinary Center of Excellence, the first of its kind in Central and Eastern Europe, focusing on the next generation of artificial intelligence and machine learning applications and quantum-centric supercomputing tools to push the frontier of neurodegeneration research, particularly Alzheimer‘s disease, by processing large-scale multidimensional biological and clinical data using powerful supercomputers and quantum methods.
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There are over 50 million people worldwide living with dementia today, and this number is expected to reach 82 million by 2030. According to the World Alzheimer Report 2020, the global annual cost of dementia is estimated to be more than US$ 1 trillion and is forecasted to double by 2030.
We believe that Europe as a whole has the most up-to-date scientific and clinical knowledge to understand the complexities of neurodegeneration and to develop new technological and therapeutic innovations. Europe has long been a major driver of global innovation but has recently lagged behind in growth sectors and in areas of innovation such as genomics, quantum computing and artificial intelligence.
CLARA will use Europe’s full potential and contribute to change.
The grand challenge of vitality and longevity of neurons The conventional approach in dementia research to explain neurodegenerative diseases such as Alzheimer's is to focus on presumed mechanisms of neuronal dysfunction leading to failure in particular neural systems. CLARA wants to be more ahead of the curve and is therefore tasking a bold new question: What are the essential conditions to maintain optimal function, vitality, and longevity of neurons for over 100 years?
Show more HideIn CLARA, cutting-edge technologies meet groundbreaking research in neurodegenerative diseases (NDs). In CLARA, we explore the complex interactions between molecular, behavioural, and clinical aspects of NDs through the integration of Quantum Computing (QC), High-Performance Computing (HPC), and Hybrid Computing (HPCQC), powered by Artificial Intelligence (AI) and Machine Learning (ML). By harnessing deep domain expertise and processing large-scale biological and clinical data, CLARA aims to advance our understanding of these transformative technologies. Our work accelerates innovation in computing, tackling real-world challenges, and ultimately benefiting society.
Show more HideCLARA serves as a catalyst for cross-institutional and interdisciplinary collaboration, bringing together the best teams from diverse institutions under a shared scientific vision. By fostering strong connections between different disciplines and research organizations, CLARA ensures a flexible, transparent, and innovative approach to governance. Built on a solid legal and scientific foundation, CLARA establishes a groundbreaking organizational platform that unites top-tier R&D&I teams from across the Czech Republic and beyond, driving innovation and excellence.
Show more HideThe International Neurodegenerative Disorders Research Center (INDRC) je soukromý neziskový výzkumný ústav sdružující přední odborníky z oblasti neurodegenerace a umělé inteligence s cílem dosáhnout průlomu v léčbě a prevenci Alzheimerovy choroby a dalších neurodegenerativních onemocnění. INDRC bylo založeno v roce 2021 jako mezinárodní pracoviště s transparentním modelem řízení a novou organizací výzkumu v rámci ekosystému angažovaných partnerů, včetně univerzit, výzkumných ústavů, klinických center a spolupracujících firem. Více informací o výzkumném ústavu najdete na webových stránkách INDRC a na sociální síti LinkedIn.
INDRC posiluje tým pro prestižní evropský grant, který představuje mezioborové centrum excelence zaměřené na použití umělé inteligence, kvantových počítačů a superpočítačů s cílem posunout hranice výzkumu lidského mozku, jeho struktury, vazeb a neurodegenerace, zejm. Alzheimerovy choroby. Díky průlomovým technologiím a vědecko-výzkumné koncepci, projekt usiluje o propojení roztříštěných oborových znalostí, rozsáhlých biologických a klinických dat, což přispěje k lepšímu porozumění vzniku a prevence daných onemocnění.
Výše úvazku: | 1,0 úvazek nebo dle dohody |
Nástup: | 1.10.2025 nebo dle dohody |
Pracovněprávní vztah: | Pracovní smlouva |
Lokalita: | Praha |
CLARA (Center for Artificial Intelligence and Quantum Computing in System Brain Research) je projektem evropského významu, který je financován z evropské výzvy Teaming for Excellence a zároveň z české části Teaming-CZ II vyhlášené Ministerstvem školství, mládeže a tělovýchovy České republiky, a to v souhrnné výši EUR 43mil. Do projektu hledáme novou kolegyni či kolegu na pozici Provozní ředitel/ka.
Máte zájem připojit se k našemu týmu? Zašlete nám do 19. 9. 2025 motivační dopis v anglickém jazyce, obsahující konkrétní zkušenosti, včetně výčtu projektů a dále strukturovaný životopis v anglickém jazyce na email clara@indrc.cz.
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The International Neurodegenerative Disorders Research Center (INDRC) is a private, not-for-profit research institute bringing together leading experts in neurodegeneration and artificial intelligence to achieve breakthroughs in the treatment and prevention of Alzheimer's disease and other neurodegenerative diseases. INDRC was established in 2021 as an international institute with a transparent governance model and a new research organization within an ecosystem of committed partners, including universities, research institutes, clinical centers and collaborating companies. For more information about the research institute, please visit the INDRC website and the social network LinkedIn.
The prestigious European CLARA grant, which is an interdisciplinary centre of excellence, focused on the use of artificial intelligence, quantum computing and supercomputing to push the boundaries of research on the human brain, its structure, and neurodegeneration, in particular Alzheimer's disease. Through breakthrough technologies and scientific research design, the project aims to bring together fragmented disciplinary knowledge, large-scale biological and clinical data to contribute to a better understanding of the origins and prevention of these diseases.
CLARA is a project of European significance and is funded by the European call Teaming for Excellence and the Czech part of Teaming-CZII announced by the Ministry of Education, Youth and Sports of the Czech Republic in total amount of EUR 43M.
We are looking for a new colleague to join the CLARA project as our Chief Operating Officer (COO).
Job Status: | Full-time or by agreement |
Starting Date: | October 1st 2025 or by agreement |
Employment Relationship: | Employment contract |
Location: | Prague |
Interested in joining our team? Please send us a cover letter in English containing specific experience, including a list of projects and a structured CV in English to clara@indrc.cz by September 19, 2025.
The International Neurodegenerative Disorders Research Center (INDRC) je soukromý neziskový výzkumný ústav sdružující přední odborníky z oblasti neurodegenerace a umělé inteligence s cílem dosáhnout průlomu v léčbě a prevenci Alzheimerovy choroby a dalších neurodegenerativních onemocnění. INDRC bylo založeno v roce 2021 jako mezinárodní pracoviště s transparentním modelem řízení a novou organizací výzkumu v rámci ekosystému angažovaných partnerů, včetně univerzit, výzkumných ústavů, klinických center a spolupracujících firem. Více informací o výzkumném ústavu najdete na webových stránkách INDRC a na sociální síti LinkedIn.
INDRC posiluje tým pro prestižní evropský grant, který představuje mezioborové centrum excelence zaměřené na použití umělé inteligence, kvantových počítačů a superpočítačů s cílem posunout hranice výzkumu lidského mozku, jeho struktury, vazeb a neurodegenerace, zejm. Alzheimerovy choroby. Díky průlomovým technologiím a vědecko-výzkumné koncepci, projekt usiluje o propojení roztříštěných oborových znalostí, rozsáhlých biologických a klinických dat, což přispěje k lepšímu porozumění vzniku a prevence daných onemocnění.
Výše úvazku: | 1,0 úvazek nebo dle dohody |
Nástup: | 1.10.2025 nebo dle dohody |
Pracovněprávní vztah: | Pracovní smlouva |
CLARA (Center for Artificial Intelligence and Quantum Computing in System Brain Research) je projektem evropského významu, který je financován z evropské výzvy Teaming for Excellence a zároveň z české části Teaming-CZ II vyhlášené Ministerstvem školství, mládeže a tělovýchovy České republiky, a to v souhrnné výši EUR 43mil. Do projektu hledáme novou kolegyni či kolegu na pozici Hlavní projektový manažer/ka.
Máte zájem připojit se k našemu týmu? Zašlete nám do 19. 9. 2025 motivační dopis v anglickém jazyce, obsahující konkrétní zkušenosti, včetně výčtu projektů a dále strukturovaný životopis v anglickém jazyce na email clara@indrc.cz.
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The International Neurodegenerative Disorders Research Center (INDRC) is a private, not-for-profit research institute bringing together leading experts in neurodegeneration and artificial intelligence to achieve breakthroughs in the treatment and prevention of Alzheimer's disease and other neurodegenerative diseases. INDRC was established in 2021 as an international institute with a transparent governance model and a new research organization within an ecosystem of committed partners, including universities, research institutes, clinical centers and collaborating companies. For more information about the research institute, please visit the INDRC website and the social network LinkedIn.
The prestigious European CLARA grant, which is an interdisciplinary centre of excellence focused on the use of artificial intelligence, quantum computing and supercomputing to push the boundaries of research on the human brain, its structure, and neurodegeneration, in particular Alzheimer's disease. Through breakthrough technologies and scientific research design, the project aims to bring together fragmented disciplinary knowledge, large-scale biological and clinical data to contribute to a better understanding of the origins and prevention of these diseases.
CLARA is a project of European significance and is funded by the European call Teaming for Excellence and the Czech part of Teaming-CZII announced by the Ministry of Education, Youth and Sports of the Czech Republic in total amount of EUR 43M.
We are looking for a new colleague to join the CLARA project as a General Project Manager.
Amount of time: | 1,0 time or by agreement |
Start date: | October 1, 2025 or by agreement |
Employment relationship: | Employment contract |
Interested in joining our team? Please send us a cover letter in English containing specific experience, including a list of projects and a structured CV in English to clara@indrc.cz by September 19, 2025.
Project title | Center for Artificial Intelligence and Quantum Computing in System Brain Research |
ID | 101136607 |
Link to Cordis | https://cordis.europa.eu/project/id/101136607 |
Acronym | CLARA |
Supported by | European Commission Granting authority: European Research Executive Agency |
Programme | EC‘s Horizon Europe Teaming for Excellence Program Call: HORIZON-WIDERA-2023-ACCESS-01 Topic: HORIZON-WIDERA-2023-ACCESS-01-01-two-stage Type of action: HORIZON Coordination and Support Actions (CSA) |
Project duration | 1 November 2024 - 31 October 2030 (72 months) |
Total budget / Eligible costs | 14 999 782.50 EUR (max grant amount) |
Coordinator | INDRC – International Neurodegenerative Disorders Research Center |
Partners | CIIRC CTU – Czech Institute of Informatics, Robotics and Cybernetics CTU in Prague VSB-TUO – Technical University of Ostrava | IT4Innovations ICRC – International Clinical Research Center, St. Anne’s University Hospital Brno PBI - Paris Brain Institute, France LRZ – Leibniz Supercomputing Centre, Bavarian Academy of Sciences and Humanities, Germany |
Main investigators |
Project title | Centrum pro umělou inteligenci a kvantové výpočty v systémovém výzkumu mozku (Center for Artificial Intelligence and Quantum Computing in System Brain Research) |
ID | CZ.02.01.01/00/23_029/0008437 |
Supported by | Ministry of Education, Youth, and Sports (MEYS) of the Czech Republic |
Programme | ESIF-MEYS Johannes Amos Comenius Programme (P JAC) Call No. 02_23_029 Teaming-CZ II |
Project duration | 1 January 2025 - 31 December 2028 (48 months) |
Total budget / Eligible costs | 699 945 064,98 CZK (approx. 29.4 mil. EUR) |
Main Beneficiary | INDRC – International Neurodegenerative Disorders Research Center |
Main investigators | CIIRC CTU – Czech Institute of Informatics, Robotics and Cybernetics CTU in Prague VSB-TUO – Technical University of Ostrava | IT4Innovations ICRC – International Clinical Research Center, St. Anne’s University Hospital Brno |
Please find below the list of deliverables with the dissemination level “Public.” Deliverables that are sensitive or confidential (i.e., intended only for members of the consortium and the EC) are not listed here. The documents have been approved by the CLARA project consortium and submitted to the EC, but they may still be undergoing approval by the European Commission. These deliverables should be considered working material. Final links to the fully approved documents will be added on a rolling basis once confirmed by the EC.
D1.5 Risk Assessment and Quality Plan
VSB-TUOD2.1 Center Core Documents
INDRCD2.2 Gender Equality Plan
INDRCD2.4 Data Management Plan (DMP)
VSB-TUOD2.5 Ethical Codex
INDRCD3.8 Tenure Track policy
CIIRC CTUD4.1 HR Strategy
INDRCD6.1 Plan for Dissemination and Exploitation Including Communication Activities
CIIRC CTUThis project has received funding from the European Union’s Horizon Europe Framework Programme under Grant Agreement No. 101136607 and has been co-funded by the European Union within the project CLARA - Center for Artificial Intelligence and Quantum Computing in System Brain Research (reg. no. CZ.02.01.01/00/23_029/0008437).
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency (REA). Neither the European Union nor the granting authority can be held responsible for them.